Citología en Base Líquida

La citología en base líquida busca evitar los resultados falsos negativos (falta de identificación de las células anormales, cuando están presentes) de la citología tradicional porque brinda mejores resultados, en la detección de las lesiones cervicales precancerosas.


La citología en base líquida está en proceso de reemplazo de la tradicional (también denominada Papanicolaou) en algunos países, y en el LABORATORIO CLÍNICO BIOREFERENCIA contamos con esta técnica. La citología en base líquida no se hace a partir de un proceso de frotis como la tradicional.

La citología es un análisis que detecta el cáncer del cuello de la matriz (útero) y de las lesiones que lo preceden. Se conoce como papanicolaou.


  1. El convencional, se toma la muestra con un cepillo, se extiende en un portaobjetos de cristal y se procede a su respectivo análisis.
  2. El procedimiento en base mediante varias etapas, se obtiene una lámina o una sola capa de células, lo que permite una mayor detección de lesiones neoplásicas o sus precursoras. La toma de la muestra es exactamente igual al método tradicional, pero el laboratorio no realiza ningún extendido, sino que introduce el escobillón del cepillo en un frasco con conservador y se hace el análisis patológico.

Ventajas de la citología en base líquida sobre la citología tradicional:

  1. Captura la totalidad de la muestra
  2. Elimina la fijación deficiente
  3. Elimina la existencia de elementos “distractores” para la interpretación patológica
  4. Distribuye en forma aleatoria las células en una monocapa
  5. En cuanto a los resultados:

– Mejora la calidad de la muestra

–Permite la realización de muestras adicionales o pruebas moleculares para la identificación de Virus del papiloma humano

Desventajas de la citología tradicional:

  1. Exceso o escasez de células en PAP convencional
  2. El cepillo puede obtener de : 250, 000- 1.2 millones de  células epiteliales
  3. Frotis muy gruesos
  4. Frotis con celularidad variable
  5. Menos del 37.5%-93.5% puede transferirse al portaobjetos, al realizar el frotis; el material restante se queda en las cerdas del cepillo y se tira a la basura
  6. El traspaso de células está sujeto a error, si las células anormales no se distribuyen de forma homogénea por toda la muestra


CompartirShare on FacebookShare on Google+Tweet about this on TwitterShare on LinkedInEmail this to someoneShare on TumblrBuffer this page
22 Diciembre, 2017

  1. I want to voice my love for your kindness giving support to persons that should have assistance with this particular idea. Your special dedication to getting the solution throughout appears to be rather valuable and has always empowered those like me to attain their desired goals. Your entire warm and helpful guideline denotes this much a person like me and far more to my colleagues. Warm regards; from everyone of us.

  2. I wish to show my passion for your kindness supporting folks that absolutely need help with this one content. Your personal commitment to passing the solution all through appears to be extraordinarily informative and have in every case encouraged women just like me to achieve their pursuits. Your helpful tutorial indicates a great deal to me and still more to my colleagues. Thanks a lot; from everyone of us.

  3. I wish to express thanks to you for rescuing me from this type of issue. As a result of scouting through the search engines and seeing basics which are not productive, I assumed my life was gone. Existing minus the answers to the difficulties you’ve fixed as a result of your main post is a crucial case, as well as the kind that would have in a wrong way affected my entire career if I hadn’t come across your web site. The talents and kindness in handling every aspect was crucial. I don’t know what I would’ve done if I hadn’t encountered such a step like this. I can also at this time look forward to my future. Thank you so much for this high quality and results-oriented guide. I will not be reluctant to recommend your web sites to any individual who should receive direction on this subject.

  4. I’m just writing to make you be aware of what a awesome discovery my friend’s girl undergone going through yuor web blog. She mastered so many details, not to mention what it’s like to have an incredible helping heart to make a number of people just fully grasp specified advanced things. You actually exceeded her expectations. I appreciate you for supplying those effective, dependable, explanatory and even unique guidance on the topic to Evelyn.

  5. My wife and i have been absolutely thankful when Louis could conclude his homework through the precious recommendations he received from your web pages. It’s not at all simplistic to simply choose to be handing out tips which usually most people may have been selling. We remember we need you to give thanks to for this. Most of the explanations you’ve made, the easy web site navigation, the relationships your site assist to foster – it’s got mostly superb, and it is letting our son in addition to us reason why that situation is pleasurable, which is certainly wonderfully important. Thank you for everything!

  6. A lot of thanks for all of the efforts on this website. Kim take interest in managing internet research and it’s easy to understand why. We all hear all about the lively medium you present valuable guidance through your website and as well as increase contribution from other people on this subject matter so our own simple princess is starting to learn a lot. Have fun with the rest of the year. You are conducting a terrific job.

  7. I simply wished to thank you so much again. I do not know what I could possibly have made to happen without the entire opinions discussed by you directly on this subject. Entirely was a very frustrating condition for me, however , viewing a new well-written strategy you processed it forced me to jump for fulfillment. I will be thankful for your advice and as well , pray you know what a powerful job your are doing teaching people by way of your site. Most probably you’ve never got to know all of us.

  8. I precisely needed to say thanks once more. I’m not certain what I could possibly have implemented in the absence of those techniques documented by you concerning such question. It became the scary problem for me, nevertheless being able to see a professional manner you solved that took me to leap with gladness. Now i’m grateful for your support and in addition hope you recognize what an amazing job your are doing training many others with the aid of your web blog. I know that you have never come across any of us.

  9. I precisely desired to say thanks again. I am not sure the things that I could possibly have made to happen without these tactics documented by you on my industry. It had been an absolute daunting case for me personally, nevertheless taking a look at the very specialised style you resolved that took me to cry over gladness. I’m happy for your guidance and then have high hopes you are aware of a great job you are always putting in teaching the others all through your website. I’m certain you haven’t come across all of us.

  10. My spouse and i ended up being so joyful Albert managed to finish off his survey with the ideas he received out of your weblog. It’s not at all simplistic just to continually be handing out tips that many some people might have been selling. And we fully understand we’ve got you to be grateful to because of that. The type of illustrations you’ve made, the easy website navigation, the relationships you make it possible to instill – it’s got most sensational, and it’s helping our son and our family believe that this content is thrilling, which is certainly seriously indispensable. Thanks for the whole lot!

Deja un comentario

Tu dirección de correo electrónico no será publicada. Los campos obligatorios están marcados con *